This Week in Startups
This Week in Startups

Dr. Mark Hyman on Function Health & GLP-1 microdosing | E2334

September 4, 2026 · 58 min

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Show notes

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Today's show:

Your doctor almost certainly isn't testing your insulin. Dr. Mark Hyman sits down with Jason to explain the broken system that Function is fixing, and what 100 million biomarkers say about how sick America actually is.

Learn why insulin beats blood sugar as an early warning for TKTKTK. Why might "normal" lab ranges be unreliable? PLUS, how does an expert like Dr. Hyman feel about GLP-1s and psychedelics?

Guests:

Dr. Mark Hyman on X: https://x.com/drmarkhyman

Function: https://www.functionhealth.com/

Relevant Links:

• The Dr. Hyman Show — https://podcasts.apple.com/us/podcast/the-dr-hyman-show/id1382804627

• Function pricing — https://www.functionhealth.com/pricing

• Ezra — the full-body MRI company Function acquired https://ezra.com/

• Galleri (GRAIL) — the multi-cancer early detection blood test — https://www.galleri.com/

• Tufts / JACC study — the source of the "93% of Americans have metabolic dysfunction" — https://now.tufts.edu/2022/07/05/only-7-american-adults-have-good-cardiometabolic-health

• American College of Cardiology — https://www.acc.org/

• Dr. Jorge Plutzky — https://www.health.harvard.edu/authors/jorge-plutzky-md

• OpenEvidence — https://www.openevidence.com/

• Stanford Metabolic Psychiatry Clinic — https://med.stanford.edu/news/all-news/2022/11/metabolic-psychiatry.html

• Stanford Medicine on the ibogaine findings → https://med.stanford.edu/news/all-news/2024/01/ibogaine-ptsd.html

• Texas SB 2308 — the $50M state investment in ibogaine trials — https://www.texastribune.org/2026/03/31/texas-ibogaine-research-clinical-trials-psychedelics/

Timestamps:

What Function actually is

Healthspan vs. sick care

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