This Week in Startups
Jason Calacanis
Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.
DEBRIEF7 min · Written and voiced by AI
Why a Do-Nothing Congress could be great for markets | E2359Nov 5, 2026 · 1 h 25 min
Why a Do-Nothing Congress could be great for markets | E2359This Week In Startups is made possible by: Every: https://every.io/ Vanta: https://www.vanta.com/twist G2i: http://G2i.co/twist Plaud: https://Plaud.ai/twist Fintrx…
DEBRIEF5 min · Written and voiced by AI
Odyssey CEO Oliver Cameron is 90% sure we live in a simulation | E2358Nov 3, 2026 · 1 h 24 min
Odyssey CEO Oliver Cameron is 90% sure we live in a simulation | E2358This Week In Startups is made possible by: Paper: https://getpaper.ai/twist G2i: https://G2i.co/twist Northwest Registered Agent…
DEBRIEF4 min · Written and voiced by AI
Binance Hacked $6.3B Stolen, DoorDash Buys Instacart For $17B, Jake Newfield from Hermetiq, + More!Oct 30, 2026 · 1 h 11 min
Binance Hacked $6.3B Stolen, DoorDash Buys Instacart For $17B, Jake Newfield from Hermetiq, + More!This Week In Startups is made possible by: Stripe: https://stripe.com/startups Rippling: https://Rippling.ai/twist Northwest Registered Agent…
DEBRIEF6 min · Written and voiced by AI
Is AI the new cigarettes? Our VC panel digs into Anthropic’s S-1 | E2356Oct 29, 2026 · 1 h 12 min
Is AI the new cigarettes? Our VC panel digs into Anthropic’s S-1 | E2356This Week In Startups is made possible by: PayPal: https://paypal.com/business The Conservation Fund: https://www.conservationfund.org/ Hostinger: https://hostinger.com/twist…
DEBRIEF5 min · Written and voiced by AI
Pregame Your Launch Before Your App Exists (w/ Amanda Bradford) | E2355Oct 26, 2026 · 57 min
Pregame Your Launch Before Your App Exists (w/ Amanda Bradford) | E2355This Week In Startups is made possible by: Odoo: https://odoo.com/twist G2i: https://g2i.co/twist Rippling: https://rippling.ai/twist Plaud: https://plaud.ai/twist Today’s show…
DEBRIEF6 min · Written and voiced by AI
OpenAI’s $1.25T Raise, Starlink Mobile & Zuck’s Tax Deal | EP 2354Oct 24, 2026 · 1 h 33 min
OpenAI’s $1.25T Raise, Starlink Mobile & Zuck’s Tax Deal | EP 2354This Week In Startups is made possible by: Plaud - https://plaud.ai/twist Sentry - https://sentry.io/twist Lightfield - https://lightfield.app Rippling - https://rippling.ai/twist…
DEBRIEF6 min · Written and voiced by AI
We asked 3 VCs: would you invest in Elizabeth Holmes’ next startup? | E2353Oct 22, 2026 · 1 h 41 min
We asked 3 VCs: would you invest in Elizabeth Holmes’ next startup? | E2353This Week In Startups is made possible by: DigitalOcean - Head to https://do.co/twist to start building on DigitalOcean's AI-Native Cloud today — and cut your AI workload costs by…
DEBRIEF6 min · Written and voiced by AI
Anthropic Gives Away 5% of Its Shares, Clone’s Muscle Robot, ElevenLabs Steals Podcaster's VoiceOct 20, 2026 · 1 h 34 min
Anthropic Gives Away 5% of Its Shares, Clone’s Muscle Robot, ElevenLabs Steals Podcaster's VoiceThis Week In Startups is made possible by: Plaud: https://plaud.ai/twist Northwest Registered Agent: https://www.northwestregisteredagent.com/twistdomain Vanta…
DEBRIEF7 min · Written and voiced by AI
Flying Cars, OpenAI Spies, Why AI Isn’t Sticking (Superhuman CEO)Oct 17, 2026 · 1 h 33 min
Flying Cars, OpenAI Spies, Why AI Isn’t Sticking (Superhuman CEO)This Week In Startups is made possible by: Lightfield: https://lightfield.app/ Every.io: https://every.io/. PayPal: https://paypal.com/business Plaud: https://Plaud.ai/twist…
DEBRIEF4 min · Written and voiced by AI
The Ex-DeepMind Researcher Taking On China’s Open Source AIOct 14, 2026 · 1 h
The Ex-DeepMind Researcher Taking On China’s Open Source AIThis Week In Startups is made possible by: Paper: getpaper.ai/twist Superhuman: https://superhuman.com/ Odoo: https://Odoo.com/twist Today’s show: Misha Laskin of Reflection AI…
DEBRIEF5 min · Written and voiced by AI
The Gadget That's Better in Crowds Than Your Phone + Ring’s Founder Before Amazon Bought It | E2349Oct 12, 2026 · 1 h 20 min
The Gadget That's Better in Crowds Than Your Phone + Ring’s Founder Before Amazon Bought It | E2349This Week In Startups is made possible by: Plaud: https://Plaud.ai/twist Northwest Registered Agent: https://www.northwestregisteredagent.com/twistdomain NetSuite…
DEBRIEF6 min · Written and voiced by AI
Jason Reacts To Japanese Founder Pitches + Fireside Chat With Yuki ShiratoOct 10, 2026 · 1 h 25 min
Jason Reacts To Japanese Founder Pitches + Fireside Chat With Yuki ShiratoThis Week In Startups is made possible by: Lightfield: https://lightfield.app/ Rippling: https://Rippling.ai/twist Upwork: http://upwork.com Today’s show: AssetHub built an AI…
Oct 8, 2026 · 1 h 19 min
What VCs Really Think About Personal AI Agents | E2347This Week In Startups is made possible by: Plaud: http://Plaud.ai/twist Odoo: http://Odoo.com/twist Northwest Registered Agent: http://www.northwestregisteredagent.com/twistdomain…
Oct 5, 2026 · 1 h 11 min
Jason Mentors The Next Generation + Why AI Is Bad at Teaching (Aristotle Interview) | E2346This Week In Startups is made possible by: Vanta: https://www.vanta.com/twist DigitalOcean: https://do.co/twist Sentry: http://sentry.io/twist Plaud: http://Plaud.ai/twist Today’s…
Oct 3, 2026 · 53 min
Inside The Startup Building Uncensored AI (Abliteration AI) | EP 2345This Week In Startups is made possible by: Every.io: http://every.io/ Northwest Registered Agent: https://www.northwestregisteredagent.com/twistdomain Odoo: http://Odoo.com/twist…
Sep 30, 2026 · 1 h 18 min
Justin Kan & Brian Chesky: The Rejections That Built Twitch and Airbnb | E2344This Week In Startups is made possible by: Plaud: http://Plaud.ai/twist CLA: https://claconnect.com/tech Sentry: http://sentry.io/twist Lightfield: http://sentry.io/twist Today’s…
Sep 28, 2026 · 41 min
Jason’s Put a $5K Bounty on His Dream Chrome Extension | E2338This Week In Startups is made possible by: Every.io: http://every.io/ Northwest Registered Agent: www.northwestregisteredagent.com/twistdomain Sentry: http://sentry.io/twist…
Sep 28, 2026 · 50 min
The 5 Companies Apple Must BuyThis Week In Startups is made possible by: PayPal - https://paypal.com/business Northwest Registered Agent - https://www.northwestregisteredagent.com/twistdomain Odoo…
Sep 25, 2026 · 1 h 26 min
A rogue OpenAI agent hacked Australia’s government. Does this matter? | E2342This Week In Startups is made possible by: https://lightfield.app/ http://getpaper.ai/twist https://conservationfund.org/ http://Plaud.ai/twist https://www.athena.com/jcal Today’s…
Sep 23, 2026 · 1 h 27 min
VCs Would Bet on Open-Source AI Over OpenAI and Anthropic | E2341This Week In Startups is made possible by: Northwest Registered Agent: https://www.northwestregisteredagent.com/twistdomain Odoo: http://Odoo.com/twist Rippling…
Sep 21, 2026 · 1 h 10 min
Elon's New Hyperloop, Trump's AI Rename, and a Model That Won't Talk | E2340This Week In Startups is made possible by: Vanta: https://www.vanta.com/twist DigitalOcean: http://do.co/twist Lightfield: https://lightfield.app/ Plaud: http://Plaud.ai/twist…
Sep 18, 2026 · 1 h 34 min
Hugging Face Co-Founder on Open-Source, Microduck, and NVIDIA | E2339This Week In Startups is made possible by: Superhuman: http://superhuman.com/ Paypal: http://paypal.launch.co Odoo: http://Odoo.com/twist Plaud: http://Plaud.ai/twist Harmonic…
Sep 18, 2026 · 1 h 34 min
Hugging Face Co-Founder on Open-Source, Microduck, and NVIDIA | E2339This Week In Startups is made possible by: Superhuman: http://superhuman.com/ Paypal: http://paypal.launch.co Odoo: http://Odoo.com/twist Plaud: http://Plaud.ai/twist Harmonic…
Sep 15, 2026 · 19 min
90% of AI prototypes never reach production (w/ Temporal's Samar Abbas) | AI BasicsThe TWiST AI Basics series is made possible by Google for Startups! Build context-aware AI workflows using DeepMind models and orchestration tools with Google for Startups' new…
Sep 14, 2026 · 1 h 11 min
Ask Jason: AI Extinction, Grok's Rogue Meme Coin & Weed Farms as Data Centers | E2337This Week In Startups is made possible by: Quo: http://quo.com/TWiST The Conservation Fund: https://conservationfund.org CLA…
Sep 11, 2026 · 1 h 13 min
The Pentagon Wants Equity in AI Startups | E2336This Week In Startups is made possible by: DigitalOcean — Want to see what building on a true AI-native platform looks like? Head to do.co/twist to start building on DigitalOcean's…
Sep 10, 2026 · 23 min
Becki DeGraw on founder vesting, advisor equity & the 4-term-sheet playThis Week In Startups is made possible by: Wilson Sonsini: https://www.wsgr.com/en/ Today's show: One of YouTube's three co-founders left for grad school and walked away with a…
Sep 9, 2026 · 1 h 21 min
Did OpenAI Steal the Navier-Stokes Solution? | E2335This Week In Startups is made possible by: Northwest Registered Agent - https://www.northwestregisteredagent.com/twistdomain NetSuite - https://www.netsuite.ai/twist Vanta…
Sep 4, 2026 · 58 min
Dr. Mark Hyman on Function Health & GLP-1 microdosing | E2334This Week In Startups is made possible by: Odoo - http://Odoo.com/twist Northwest Registered Agent - https://www.northwestregisteredagent.com/twistdomain Rippling…
Sep 3, 2026 · 18 min
Becki DeGraw on spinouts, IP licensing & clean exits | Wilson Sonsini Startup Legal BasicsThis Week In Startups is made possible by: Wilson Sonsini Today's show: Spinouts are everywhere right now, and most founders get the cap table wrong. Jason sits down with Becki…
Sep 2, 2026 · 1 h 20 min
VC experts on why Physical AI funding is heating up | E2333VC experts on why Physical AI funding is heating up | E2333 This Week In Startups is made possible by: partner 1 - link partner 2 - link partner 3 - link Today's show: Are we one…
Aug 31, 2026 · 1 h 7 min
Are AI Agents forming "civilizations" or is this just a psy op? | 2332This Week In Startups is made possible by: Northwest Registered Agent https://northwestregisteredagent.com/twistdomain CLA https://claconnect.com/withyou Rippling…
Aug 28, 2026 · 1 h 48 min
Breaking down Nvidia's Hugging Face and Poolside bets | E2331This Week In Startups is made possible by: DigitalOcean https://do.co/twist Every.io https://every.io PayPal https://paypal.launch.co Today's show: *Nvidia agreed to buy Hugging…
Aug 26, 2026 · 1 h 31 min
Bill Gates foresees massive AI job loss: these VCs disagree | E2330This Week In Startups is made possible by: Lightfield https://lightfield.app Northwest Registered Agent https://www.northwestregisteredagent.com/twistdomain Rippling…
Aug 25, 2026 · 25 min
You Can't Fire a VC From Your Board: Here's Why | Wilson Sonsini Startup Legal BasicsToday's show: Can a founder actually fire a board member? Short answer: almost never. And the reason why may surprise a lot of founders. On this edition of Legal Basics, Wilson…
Aug 25, 2026 · 1 h 20 min
China wants you to cheer for the robots taking your job | E2329This Week In Startups is made possible by: Odoo https://Odoo.com/twist Quo https://quo.com/TWiST Conservation Fund https://conservationfund.org how old a movie has to be for me to…
Aug 21, 2026 · 1 h 9 min
Open source is going to win it all: Harvey proves it | E2328This Week In Startups is made possible by: Superhuman https://Superhuman.com Sentry https://sentry.io/twist Lightfield https://lightfield.app Today's show: Jason's been saying it…
Aug 20, 2026 · 21 min
Taste is the new programming language (w/ Astrocade CEO Amir Sadeghian) | AI BasicsThe TWiST AI Basics series is made possible by Google Cloud! Build context-aware AI workflows using DeepMind models and orchestration tools with Google for Startups' new Startup…
Aug 19, 2026 · 54 min
Neurosymbolic AI outperforms chatbots and product search | E2327This Week In Startups is made possible by: Vanta https://www.vanta.com/twist Agree https://agree.com YSecurity https://YSecurity.io/TWIST Today's show: Frontier AI models can ace…
Aug 17, 2026 · 1 h 25 min
Bittensor creator Const on Affine, dTAO, "mining reasoning," and more | E2326This Week In Startups is made possible by: Northwest Registered Agent https://northwestregisteredagent.com/twist DigitalOcean https://do.co/twist Odoo https://Odoo.com/twist…
Aug 15, 2026 · 1 h 20 min
What we'll learn from Anthropic's $2-$3T IPO | E2325This Week In Startups is made possible by: PayPal Open https://paypal.launch.co CLA https://claconnect.com/withyou Odoo https://Odoo.com/twist Today's show: *Anthropic is likely…
Aug 12, 2026 · 1 h 4 min
These robots could cut delivery costs by 80% | Next UnicornsThese robots could cut delivery costs by 80% | Next Unicorns This Week In Startups is made possible by: Squarespace https://squarespace.com/twist Northwest Registered Agent…
Aug 11, 2026 · 1 h 20 min
Zuck's AI manifesto is a data center PR masterclass | E2323This Week In Startups is made possible by: Every.io https://every.io NetSuite https://NetSuite.ai/TWIST YSecurity https://YSecurity.io/TWIST Today's show: *Meta chief Mark…
Aug 7, 2026 · 1 h 18 min
How AI splits startups into winners and losers | E2322This Week In Startups is made possible by: DigitalOcean https://do.co/twist Sentry https://sentry.io/twist Lightfield https://lightfield.app Today's show: A hedge fund just blew up…
Aug 5, 2026 · 1 h 13 min
Airtable's 80% off value crash: VCs explain why it's still a win | E2321This Week In Startups is made possible by: Vanta https://www.vanta.com/twist Agree https://agree.com Odoo https://Odoo.com/twist Today's show: *Airtable just sold for $2.25…
Aug 3, 2026 · 1 h 2 min
How Bespoke faked AI until it actually worked (w/ Akemi Tsunagawa) | E2320This Week In Startups is made possible by: Odoo https://Odoo.com/twist Quo https://quo.com/TWiST Northwest Registered Agent https://northwestregisteredagent.com/twist Today's show…
Jul 31, 2026 · 1 h 15 min
Why AI has no taste and how to fix it (w/ Thais Castello Branco) | E2319This Week In Startups is made possible by: YSecurity https://YSecurity.io/TWIST MongoDB https://MongoDB.com/ai Odoo https://Odoo.com/twist Today's show: AI models can solve…
Jul 29, 2026 · 1 h 26 min
Banning Chinese robots isn't regulatory capture | E2318This Week In Startups is made possible by: Northwest Registered Agent- NorthwestRegisteredAgent.com/twist Odoo - Odoo.com/twist MongoDB - MongoDB.com/ai Today's show: The FCC's…
Jul 27, 2026 · 44 min
While other cultivated meat companies are collapsing, this one turned a profit | E2317This Week In Startups is made possible by: Every.io https://every.io MongoDB https://MongoDB.com/ai Agree https://agree.com Today's show: *Most lab-grown meat companies have…
Jul 24, 2026 · 45 min
Why quantum has been "10 years away" for 30 years | E2316This Week In Startups is made possible by: PayPal Open https://paypalopen.com DigitalOcean https://do.co/twist Rippling https://Rippling.ai/twist Today's show: *For three decades…
Jul 22, 2026 · 1 h 12 min
Why this longevity startup raised in Japan, not Silicon Valley | TWiST Tokyo | E2315This Week In Startups is made possible by: Sentry https://sentry.io/twist Agree https://agree.com Northwest Registered Agent https://northwestregisteredagent.com/twist Today's…
Jul 20, 2026 · 42 min
The AI Securing Your Workforce Before a Mistake Ever Becomes a Breach | E2314This Week In Startups is made possible by: Vanta https://www.vanta.com/twist Superhuman https://superhuman.com YSecurity https://YSecurity.io/TWIST Today's show: *Cybersecurity has…
Jul 17, 2026 · 47 min
The dawn of surgery bots + buy a home for $250 (w/ Andromeda & Mogul) | E2313The dawn of surgery bots + buy a home for $250 (w/ Andromeda & Mogul) | E2313 This Week In Startups is made possible by: Northwest Registered Agent…
Jul 15, 2026 · 1 h 14 min
A Startup Is Trying to Buy PayPal… Craziest Deal of 2026! | E2312This Week In Startups is made possible by: MongoDB - MongoDB.com/ai Rippling - Rippling.ai/twist Agree.com - agree.com Today's show: Hustle Fund's Eric Bahn and Chapter One's Jeff…
Jul 13, 2026 · 1 h 30 min
Jason turned $11 and one tweet into 1.1M views | E2311This Week In Startups is made possible by: Quo https://quo.com/TWiST PayPal Open https://paypalopen.com Northwest Registered Agent https://northwestregisteredagent.com/twist…
Jul 10, 2026 · 1 h 1 min
Danny Bernstein left Big Tech to fund farm-bots | E2310This Week In Startups is made possible by: NetSuite https://NetSuite.ai/TWIST Squarespace https://squarespace.com/twist YSecurity https://YSecurity.io/TWIST Today's show: *America…
Jul 8, 2026 · 1 h 6 min
Why Data Is the Next $1 Trillion MarketThis Week In Startups is made possible by: Digital Ocean - do.co/twist Agree.com - agree.com Every.io - every.io. Today's show: How many startups matter in tech? Fewer than you…
Jul 6, 2026 · 58 min
$100T is managed by "human duct tape" | E2308This Week In Startups is made possible by: Northwest Registered Agent https://northwestregisteredagent.com/twist Vanta https://www.vanta.com/twist Sentry https://sentry.io/twist…
Jul 1, 2026 · 1 h 14 min
Why the VC Hype Cycle Always Gets It Wrong | VC Roundtable | E2307This Week In Startups is made possible by: CLA - www.claconnect.com/withyou Northwest Registered Agent - www.northwestregisteredagent.com/twist Agree.com - www.agree.com Today's…
Jun 29, 2026 · 1 h 12 min
Chamath on why young people need more agency, risk, and adventureThis Week In Startups is made possible by: Plaud https://Plaud.ai/twist Shopify https://shopify.com/twist LinkedIn Jobs https://LinkedIn.com/twist Northwest Registered Agent…
Jun 27, 2026 · 1 h 30 min
Why F1 Teams are Replacing Wind Tunnels with Smart Tape | E2305This Week In Startups is made possible by: Plaud - https://Plaud.ai/twistSentry - https://sentry.io/twistNorthwest Registered…
Jun 24, 2026 · 1 h 9 min
Why the Future of Video Games is Moving Back to the Dinner TableThis Week In Startups is made possible by: Deel - deel.com/twist Northwest Registered Agent - northwestregisteredagent.com/twist LinkedIn - linkedIn.com/twist Today's show: Jason…
Jun 22, 2026 · 1 h 3 min
The hottest running app has nothing to do with speed | E2303This Week In Startups is made possible by:Agree - https://agree.comQuo - https://quo.com/TWiSTSuperhuman - https://superhuman.comToday's show:In this double-header, Jason and Lon…
Jun 18, 2026 · 1 h 41 min
Why SpaceX Buying Cursor Changes EverythingThis Week In Startups is made possible by: Deel - deel.com/twist LinkedIn - linkedIn.com/twist Northwest Registered Agent - northwestregisteredagent.com/twistPlaud…
Jun 15, 2026 · 1 h 41 min
The Startup Building the First Hotel on the Moon…This Week In Startups is made possible by: Every.io - visit every.io Sentry.io - sentry.io/twist Vanta - vanta.com/twist Today's show: The next SpaceX won't be building rockets…
Jun 13, 2026 · 1 h 20 min
SpaceX IPO Day: What Wall St. and the media missed | E2300This Week In Startups is made possible by: Plaud https://Plaud.ai/twist Pilot https://pilot.com/twist Agree https://agree.com IM8 Health https://IM8health.com/twist After watching…
Jun 10, 2026 · 1 h 8 min
Why the most expensive Seed deals are the cheapest | E2299This Week In Startups is made possible by: NetSuite - Netsuite.com/TWiST Deel - Deel.com/TWiST Squarespace - Squarespace.com/TWiST Two days before SpaceX launches the largest IPO…
Jun 8, 2026 · 1 h
The AI Tutor That Makes Kids Actually Think | E2298The AI Tutor That Makes Kids Actually Think | E2298 This Week In Startups is made possible by: Northwest Registered Agent https://northwestregisteredagent.com/twist LinkedIn Jobs…
Jun 6, 2026 · 1 h 33 min
Anthropic wants to slow AI down and Bernie wants 50%: JCal Reacts | E2297This Week In Startups is made possible by: Grasshopper Bank https://grasshopper.bank/twist Vanta https://www.vanta.com/twist Render https://render.com/twist Plaud…
Jun 3, 2026 · 1 h 2 min
The project SpaceX's first employee raised $500M forThis Week In Startups is made possible by: Northwest Registered Agent - NorthwestRegistereAagent.com/TWIST Every - Every.io Sentry - Sentry.io/TWIST Today's show: Want to get to…
Jun 1, 2026 · 1 h 6 min
This Startup Fused Human Brain Cells with Silicon Chips | E2295This Week In Startups is made possible by: Deel https://deel.com/twist Quo https://quo.com/TWiST LinkedIn Jobs https://LinkedIn.com/twist Today's show: Cortical Labs is the world's…
May 29, 2026 · 58 min
How to Raise a Seed Round in 2026: Ask Jason | E2294This Week In Startups is made possible by: Grasshopper Bank https://grasshopper.bank/twistLinkedIn Jobs https://LinkedIn.com/twistNorthwest Registered Agent…
May 27, 2026 · 1 h 1 min
The Drone Company Quietly Taking Over DeliveryThis Week In Startups is made possible by: Render - render.com/twist Deel - deel.com/twist Northwest Registered Agent - northwestregisteredagent.com/twist Today's show: The…
May 23, 2026 · 1 h 47 min
From hypercars to cruise missiles: Lukas Czinger on the future of US defense | E2292This Week In Startups is made possible by: Every.io https://every.io Shopify https://shopify.com/twist Render https://render.com/twist Plaud https://Plaud.ai/twist Today's show…
May 20, 2026 · 1 h 34 min
Avi Patel on the startup that copied Kled and why he called out General Catalyst by name | E2291This Week In Startups is made possible by: Grasshopper Bank - https://grasshopper.bank/twist LinkedIn - https://linkedIn.com/twist Northwest Registered Agent…
May 18, 2026 · 1 h 9 min
Why does Gen Z hate AI?This Week In Startups is made possible by: Vanta - Vanta.com/TWIST Sentry - Sentry.io/TWIST Deel - Deel.com/TWIST Today's show: AI is the villain of the 2026 commencement cycle…
May 15, 2026 · 1 h 13 min
The Self-Driving Startup Nobody Saw Coming | E2289This Week In Startups is made possible by: IM8 Health: IM8health.com/TWIST Squarespace: Squarespace.com/TWIST Render - Render.com/TWIST Self-driving just stopped being a science…
May 13, 2026 · 1 h 25 min
How Many Startups Will Survive OpenAI? | E2288This Week In Startups is made possible by:Pilot - https://Pilot.com/TWISTGrasshopper Bank - https://Grasshopper.bank/TWISTQuo - https://Quo.com/TWiSTPlaud…
May 13, 2026 · 1 h 8 min
How the 1% Will Own Compute (and What It Means for You)The future of AI isn't a smarter chatbot. It's a model that watches your screen, listens to the room, and acts on what it sees. We dug into Thinking Machines' new interaction…
May 11, 2026 · 1 h 23 min
Cerebras's IPO goes vertical, and the death of OpenClaw? | E2287Today's show: Cerebras just jacked its IPO range to $150–$160 a share, OpenAI bought a consulting firm to seed its $4 billion private-equity joint venture, and a startup in Oakland…
May 9, 2026 · 1 h 12 min
5,000+ Tech Workers Laid Off This Week. It's Just The Beginning. | E2286This Week In Startups is made possible by: IM8 Health - https://IM8health.com/TWIST Every - Every.io Sentry - https://Sentry.io/TWIST Banks don't want to hand over their data to AI…
May 6, 2026 · 1 h 24 min
The end of Venture Capital? (VC Roundtable) | E2285This Week In Startups is made possible by: Grasshopper Bank - https://grasshopper.bank/twist PaperOS - https://paperos.com/twist LinkedIn Jobs - https://linkedIn.com/twistPlaud…
May 5, 2026 · 1 h 38 min
Naval's GP, Ankur Nagpal, Breaks Down The Viral "USVC" Fund | E2284This Week In Startups is made possible by: Render - render.com/twist Vanta - vanta.com/twist Northwest Registered Agent - northwestregisteredagent.com/twist Have you wanted to…
May 1, 2026 · 1 h 10 min
Can an AI Agent Legally Own a Company? Christian van der Henst's Wild Experiment| E2283This Week In Startups is made possible by: Pilot - https://pilot.com/twist Shopify - https://shopify.com/twist Grasshopper Bank - https://grasshopper.bank/twist Today's show: An AI…
Apr 30, 2026 · 23 min
Mastering AI Video Marketing w/ Magnific CEO Joaquín Cuenca Abela | AI BasicsThe TWiST AI Basics series is made possible by Google Cloud!Check out Google Cloud's new report, "Future of AI: Perspectives on generative media for startups," Featuring thoughts…
Apr 29, 2026 · 56 min
The $10M+ Bet on a Beanie That Reads Your Brain | Sabi & the Future of BCI | E2282This Week In Startups is made possible by: Render - https://Render.com/TWIST Northwest Registered Agent - https://NorthwestRegisteredAgent.com/TWIST LinkedIn Jobs…
Apr 28, 2026 · 53 min
China Kills Meta / Manus Deal (Story Of The Year) | E2281This Week In Startups is made possible by: IM8 Health - IM8health.com/twist Sentry - Sentry.io/twist Deel - Deel.com/twistPlaud - https://Plaud.ai/twist What's the technology story…
Apr 25, 2026 · 50 min
Naval's $500 VC fund, the Maduro Polymarket scandal, and NYT defends theft and murder | E2280This Week In Startups is made possible by: Northwest Registered Agent - https://northwestregisteredagent.com/twist LinkedIn Jobs - https://LinkedIn.com/twist Today's show: It's a…
Apr 25, 2026 · 59 min
The Defense Tech Startup YC Kicked Out of a Meeting is Now Arming America | E2280This Week In Startups is made possible by: Northwest Registered Agent - https://northwestregisteredagent.com/twist Render - https://render.com/twist Agree - https://agree.com Ro…
Apr 22, 2026 · 1 h 14 min
SpaceX and Cursor team up to topple Claude Code | E2279This Week In Startups is made possible by: LinkedIn Jobs - linkedIn.com/twist Grasshopper Bank - grasshopper.bank/twist Notion - notion.com Today's show: This week, SpaceX…
Apr 21, 2026 · 1 h 17 min
Why Your Company Should Own Its AI Model | E2278This Week In Startups is made possible by: Quo - https://quo.com/TWiST Vanta - https://vanta.com/twist Pilot - https://pilot.com/twist Plaud - https://Plaud.ai/twist Today's show…
Apr 18, 2026 · 1 h 47 min
3D-Printed Homes for $99K: ICON's Jason Ballard on the future of housing | E2277This Week In Startups is made possible by:IM8 Health - https://IM8health.com/twist Grasshopper Bank - https://grasshopper.bank/twist Northwest Registered Agent…
Apr 15, 2026 · 1 h 3 min
This 22-Year-Old Built TikTok for Mobile Games, and It's Growing Fast | E2276This Week In Startups is made possible by: LinkedIn Jobs - LinkedIn.com/twist Every.io - every.io Render - render.com/twist Today's show: *Imagine scrolling through mobile games…
Apr 14, 2026 · 1 h 19 min
Bittensor's (alleged) $10M rug pull (feat. Mark Jeffrey) | E2275This Week In Startups is made possible by: Sentry - https://sentry.io/twist Deel - https://deel.com/twist Netsuite - https://netsuite.com/twist Plaud - https://Plaud.ai/twist…
Apr 11, 2026 · 1 h 22 min
Bittensor Drama! TAO down 15%! | E2274This Week In Startups is made possible by: Pilot - https://pilot.com/TWIST Squarespace -https://squarespace.com/TWIST Northwest Registered Agent…
Apr 9, 2026 · 1 h 17 min
Anthropic's Mythos is a cyber-weapon, so you can't have it | E2273Anthropic just built a model so dangerous, they're not even going to release it (for now). On TWiST, Jason, Alex, and Neurometric CEO Rob May discuss whether or not this is just…
Apr 7, 2026 · 1 h 19 min
3 AI Agents That Actually Replaced Human Jobs | E2272Anthropic just pulled the plug on Claude subscriptions for OpenClaw and every third party agentic tool. So Jason and Lon welcome back three of our top TWiST OpenClaw experts to…
Apr 3, 2026 · 1 h 21 min
AI Rebuilt Every YC W26 Startup. Should Founders Be Scared? | E2271This Week In Startups is made possible by: Deel - deel.com/twist Grasshopper Bank - grasshopper.bank/twist Render - render.com/twist Plaud - Plaud.ai/twist An AI "holding company"…
Apr 2, 2026 · 30 min
How 3 CEOs Use AI to Run $10B in Companies | This Week in AIThis Week in AI, JCal sits down with three CEOs building the infrastructure, intelligence, and interfaces for the next era of AI: Jeremy Fraenkel (CEO, Fundamental), Victor…
Apr 1, 2026 · 1 h 28 min
Venture Roundtable: SpaceX IPO, AI's PR Crisis, and the Defense Tech Bubble | E2270This Week In Startups is made possible by: PaperOS - https://PaperOS.com/twist Northwest Registered Agent- https://northwestregisteredagent.com/twist Every.io - https://Every.io…
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